منابع مشابه
Secretion: Kiss and Run Caught on Film
Recent results have provided graphic support for the hypothesis that vesicle secretion involves a 'kiss-and-run' mechanism. Evanescent field microscopy has shown that, during exocytosis, intravesicular markers escape without collapse of the vesicular membrane into the surface membrane and that the empty vesicle is immediately retrieved back into the cell.
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New measurements show that the entire transmitter contents of a dense-core vesicle can be released within a second through a narrow fusion pore that opens transiently. With other results, this raises the possibility that some dense core vesicles may, like small synaptic vesicles, undergo immediate recycling.
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Mycobacterium tuberculosis and Mycobacterium marinum are thought to exert virulence, in part, through their ability to lyse host cell membranes. The type VII secretion system ESX-1 [6-kDa early secretory antigenic target (ESAT-6) secretion system 1] is required for both virulence and host cell membrane lysis. Both activities are attributed to the pore-forming activity of the ESX-1-secreted subs...
متن کاملTests for growth hormone secretion.
Tests for growth hormone secretion SIR,-We were interested in the correspondence between Dr Addy and Professor Brook and Dr Hindmarsh on detecting organic illness through assessment of height velocity .' 2 The question, however, is academic and their arguments theoretical since, as we have recently shown, the assessment of height velocity in individuals is so imprecise as to be clinically meani...
متن کاملTests for growth hormone secretion.
Tests for growth hormone secretion SIR,-Professor Brook and Dr Hindmarsh claim that children growing at a less than 3rd centile velocity carry a 97% chance of showing an abnormality on investigation.' In a leading article in the British Medical Journal in 1986 they wrote 'If a third centile velocity is chosen for immediate action the chances of investigating a normally growing child are only 3%...
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ژورنال
عنوان ژورنال: Nature
سال: 2016
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature18446